As we get older the collagen in the skin, the number of elastin and fibroblasts are reduced. Fibroblasts are adult stem cells of skin. Reduction of the amount and productivity of fibroblasts in skin may cause reduced productivity and thinning in support tissues. Hence water holding capacity of skin moisture decreases, begins to dry. Balance of producing color pigments in the skin are destroyed. Therefore, resistance is reduced to skin damage, and symptoms of aging begin to manifest themselves on the skin. The sagging and wrinkles in the skin turn into stable is also a result of all of this process.